[14] Santos Laguna 2-2 Toluca [5] 2021-10-25 00:06
Estadio: Estadio TSM Corona Round: 15
Árbitro: Jorge Isaac Rojas Castillo Home Manager: Guillermo Almada Away Manager: Hernan Cristante
Head to Head
| México - Liga MX | 2021/04/19 00:00 | Santos Laguna v Toluca | W | 3-1 |
| México - Liga MX | 2020/09/20 17:00 | Toluca v Santos Laguna | W | 1-2 |
| México - Liga MX | 2019/11/24 18:00 | Toluca v Santos Laguna | D | 2-2 |
| México - Liga MX | 2019/02/25 00:06 | Santos Laguna v Toluca | W | 4-0 |
| México - Liga MX | 2018/09/02 17:00 | Toluca v Santos Laguna | L | 2-1 |
| México - Liga MX | 2018/05/21 00:00 | Toluca v Santos Laguna | D | 1-1 |
| México - Liga MX | 2018/05/18 01:00 | Santos Laguna v Toluca | W | 2-1 |
| México - Liga MX | 2018/02/18 18:00 | Toluca v Santos Laguna | L | 2-0 |
| México - Copa MX | 2018/02/08 02:30 | Toluca v Santos Laguna | L | 2-0 |
| México - Copa MX | 2018/01/25 01:00 | Santos Laguna v Toluca | W | 2-1 |
| México - Liga MX | 2017/09/10 23:30 | Santos Laguna v Toluca | D | 0-0 |
| México - Liga MX | 2017/05/14 02:00 | Toluca v Santos Laguna | W | 1-3 |
| México - Liga MX | 2017/05/11 02:30 | Santos Laguna v Toluca | L | 1-4 |
| México - Liga MX | 2017/05/07 23:00 | Santos Laguna v Toluca | D | 2-2 |
| México - Liga MX | 2016/11/20 18:00 | Toluca v Santos Laguna | W | 1-2 |
| México - Liga MX | 2016/04/02 02:30 | Toluca v Santos Laguna | D | 0-0 |
| México - Liga MX | 2015/10/04 00:00 | Santos Laguna v Toluca | D | 0-0 |
| México - Liga MX | 2015/02/15 18:00 | Toluca v Santos Laguna | D | 2-2 |
| México - Liga MX | 2014/08/23 02:30 | Santos Laguna v Toluca | W | 3-0 |