| Australia - Victoria - Liga sub-21 | 2022/05/14 05:00 | Melbourne Knights sub-21 v Port Melbourne sub-21 | W | 0-1 |
| Australia - Victoria - Liga sub-21 | 2021/02/27 04:00 | Port Melbourne sub-21 v Melbourne Knights sub-21 | L | 0-4 |
| Australia - Victoria - Liga sub-21 | 2022/08/12 08:15 | Bentleigh Greens sub-21 v Port Melbourne sub-21 | W | 1-2 |
| Australia - Victoria - Liga sub-21 | 2022/07/30 09:30 | Port Melbourne sub-21 v South Melbourne sub-21 | L | 2-3 |
| Australia - Victoria - Liga sub-21 | 2022/07/23 02:15 | Avondale sub-21 v Port Melbourne sub-21 | L | 1-0 |
| Australia - Victoria - Liga sub-21 | 2022/07/16 09:30 | Port Melbourne sub-21 v Dandenong City SC sub-21 | W | 5-2 |
| Australia - Victoria - Liga sub-21 | 2022/07/09 09:30 | Port Melbourne sub-21 v Heidelberg Utd sub-21 | W | 3-1 |
| Australia - Victoria - Liga sub-21 | 2022/07/02 06:00 | Altona Magic sub-21 v Port Melbourne sub-21 | W | 0-4 |
| Australia - Victoria - Liga sub-21 | 2022/06/25 09:30 | Port Melbourne sub-21 v Oakleigh Cannons sub-21 | L | 0-1 |
| Australia - Victoria - Liga sub-21 | 2022/06/18 07:00 | Dandenong Thunder SC sub-21 v Port Melbourne sub-21 | W | 2-4 |
| Australia - Victoria - Liga sub-21 | 2022/08/13 05:00 | Melbourne Knights sub-21 v Altona Magic sub-21 | L | 0-1 |
| Australia - Victoria - Liga sub-21 | 2022/08/09 09:00 | Melbourne Knights sub-21 v Green Gully sub-21 | L | 1-4 |
| Australia - Victoria - Liga sub-21 | 2022/07/29 08:30 | Oakleigh Cannons sub-21 v Melbourne Knights sub-21 | W | 1-4 |
| Australia - Victoria - Liga sub-21 | 2022/07/23 05:00 | Melbourne Knights sub-21 v Dandenong Thunder SC sub-21 | W | 2-1 |
| Australia - Victoria - Liga sub-21 | 2022/07/16 02:30 | Eastern Lions sub-21 v Melbourne Knights sub-21 | L | 3-1 |
| Australia - Victoria - Liga sub-21 | 2022/07/02 06:00 | Hume City sub-21 v Melbourne Knights sub-21 | L | 3-0 |
| Australia - Victoria - Liga sub-21 | 2022/06/25 05:00 | Melbourne Knights sub-21 v St Albans Saints sub-21 | D | 1-1 |
| Australia - Victoria - Liga sub-21 | 2022/06/19 03:00 | Heidelberg Utd sub-21 v Melbourne Knights sub-21 | W | 1-4 |