[9] Santos Laguna 2-1 León [12] 2022-08-19 00:00
Estadio: Estadio TSM Corona Round: 9
Árbitro: Victor Alfonso Caceres Hernandez Home Manager: Eduardo Fentanes Away Manager: Renato Manuel Alves Paiva
Head to Head
| México - Liga MX | 2022/04/25 00:00 | Santos Laguna v León | D | 1-1 |
| México - Liga MX | 2021/08/22 00:00 | León v Santos Laguna | D | 1-1 |
| México - Liga MX | 2021/03/22 01:06 | Santos Laguna v León | L | 1-2 |
| México - Liga MX | 2020/11/03 03:00 | León v Santos Laguna | L | 2-1 |
| México - Liga MX | 2020/01/20 00:45 | Santos Laguna v León | W | 3-2 |
| México - Liga MX | 2019/08/29 00:00 | León v Santos Laguna | D | 2-2 |
| México - Liga MX | 2019/03/03 01:00 | León v Santos Laguna | L | 3-0 |
| México - Liga MX | 2018/09/16 21:00 | Santos Laguna v León | W | 3-0 |
Home History
| México - Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | L | 2-0 |
| México - Liga MX | 2022/08/07 02:05 | Santos Laguna v Cruz Azul | W | 4-0 |
| México - Liga MX | 2022/08/01 00:05 | Santos Laguna v Atlas | W | 1-0 |
| México - Liga MX | 2022/07/23 22:00 | Toluca v Santos Laguna | L | 2-1 |
| México - Liga MX | 2022/07/17 00:05 | Santos Laguna v Chivas de Guadalajara | D | 1-1 |
| México - Liga MX | 2022/07/09 02:05 | Puebla v Santos Laguna | L | 1-0 |
| México - Liga MX | 2022/07/04 00:05 | Santos Laguna v Monterrey | W | 4-3 |
| América - Amistosos | 2022/06/19 01:11 | Monterrey v Santos Laguna | W | 0-1 |
Away History
| México - Liga MX | 2022/08/13 22:00 | León v Mazatlán F.C. | L | 0-3 |
| México - Liga MX | 2022/08/07 00:00 | Monterrey v León | L | 5-1 |
| México - Liga MX | 2022/08/01 02:05 | León v Club América | W | 3-2 |
| México - Liga MX | 2022/07/27 02:05 | León v Toluca | L | 0-1 |
| México - Liga MX | 2022/07/21 02:05 | Chivas de Guadalajara v León | D | 0-0 |
| México - Liga MX | 2022/07/16 00:00 | Puebla v León | D | 1-1 |
| México - Liga MX | 2022/07/10 00:00 | León v Pumas de la UNAM | D | 3-3 |
| México - Liga MX | 2022/07/03 22:00 | Atlético San Luis v León | W | 1-2 |