[12] Brest 1-0 Saint-Étienne [20] 2021-12-01 18:00
Estadio: Estadio Francis-Le Ble Round: 16
Árbitro: Mikael Lesage Home Manager: Michel Der Zakarian Away Manager: Claude Puel
Head to Head
| Francia - Ligue 1 | 2021/04/24 11:00 | Saint-Étienne v Brest | W | 1-2 |
| Francia - Ligue 1 | 2020/11/21 16:00 | Brest v Saint-Étienne | W | 4-1 |
| Francia - Ligue 1 | 2020/02/16 16:00 | Brest v Saint-Étienne | W | 3-2 |
| Francia - Ligue 1 | 2019/08/18 13:00 | Saint-Étienne v Brest | D | 1-1 |
Home History
| Francia - Ligue 1 | 2021/11/28 14:00 | Burdeos v Brest | W | 1-2 |
| Francia - Ligue 1 | 2021/11/21 12:00 | Brest v Lens | W | 4-0 |
| Francia - Ligue 1 | 2021/11/07 14:00 | Lorient v Brest | W | 1-2 |
| Francia - Ligue 1 | 2021/10/31 16:00 | Brest v Mónaco | W | 2-0 |
| Francia - Ligue 1 | 2021/10/23 19:00 | Lille v Brest | D | 1-1 |
| Francia - Ligue 1 | 2021/10/17 13:00 | Brest v Reims | D | 1-1 |
| Francia - Ligue 1 | 2021/10/02 19:00 | Niza v Brest | L | 2-1 |
| Francia - Ligue 1 | 2021/09/26 13:00 | Brest v Metz | L | 1-2 |
Away History
| Francia - Ligue 1 | 2021/11/28 12:00 | Saint-Étienne v Paris St. Germain | L | 1-3 |
| Francia - Ligue 1 | 2021/11/21 14:00 | Troyes v Saint-Étienne | W | 0-1 |
| Francia - Ligue 1 | 2021/11/07 14:00 | Saint-Étienne v Clermont Foot | W | 3-2 |
| Francia - Ligue 1 | 2021/10/30 15:00 | Metz v Saint-Étienne | D | 1-1 |
| Francia - Ligue 1 | 2021/10/22 19:00 | Saint-Étienne v Angers | D | 2-2 |
| Francia - Ligue 1 | 2021/10/17 13:00 | Estrasburgo v Saint-Étienne | L | 5-1 |
| Francia - Ligue 1 | 2021/10/03 18:45 | Saint-Étienne v Lyon | D | 1-1 |
| Francia - Ligue 1 | 2021/09/25 15:00 | Saint-Étienne v Niza | L | 0-3 |