Head to Head
| MLB | 2021/05/29 00:10 | SD Padres v HOU Astros | W | 10-3 |
| MLB | 2020/08/23 20:10 | HOU Astros v SD Padres | W | 3-5 |
| MLB | 2020/08/23 01:10 | HOU Astros v SD Padres | W | 2-13 |
| MLB | 2020/08/22 01:10 | HOU Astros v SD Padres | W | 3-4 |
| MLB | 2018/04/08 18:10 | SD Padres v HOU Astros | L | 1-4 |
| MLB | 2018/04/07 23:10 | SD Padres v HOU Astros | L | 0-1 |
| MLB | 2018/04/07 00:10 | SD Padres v HOU Astros | W | 4-1 |
| MLB Exhibition | 2016/03/27 19:00 | SD Padres v HOU Astros | W | 21-6 |
Home History
| MLB | 2021/05/29 00:10 | SD Padres v HOU Astros | W | 10-3 |
| MLB | 2021/05/27 17:10 | SD Padres v MIL Brewers | L | 5-6 |
| MLB | 2021/05/26 23:40 | SD Padres v MIL Brewers | W | 2-1 |
| MLB | 2021/05/25 23:40 | SD Padres v MIL Brewers | W | 7-1 |
| MLB | 2021/05/24 23:40 | SD Padres v MIL Brewers | L | 3-5 |
| MLB | 2021/05/23 20:10 | SEA Mariners v SD Padres | W | 2-9 |
| MLB | 2021/05/23 00:40 | SEA Mariners v SD Padres | W | 4-6 |
| MLB | 2021/05/22 02:10 | SEA Mariners v SD Padres | W | 1-16 |
Away History
| MLB | 2021/05/29 00:10 | SD Padres v HOU Astros | L | 10-3 |
| MLB | 2021/05/26 23:40 | LA Dodgers v HOU Astros | W | 2-5 |
| MLB | 2021/05/26 00:10 | LA Dodgers v HOU Astros | L | 9-2 |
| MLB | 2021/05/23 18:35 | HOU Astros v TEX Rangers | L | 2-3 |
| MLB | 2021/05/22 20:05 | HOU Astros v TEX Rangers | L | 4-8 |
| MLB | 2021/05/22 00:05 | HOU Astros v TEX Rangers | L | 5-7 |
| MLB | 2021/05/20 19:37 | HOU Astros v OAK Athletics | W | 8-4 |
| MLB | 2021/05/20 01:40 | HOU Astros v OAK Athletics | W | 8-1 |