[2] Club Libertad 1-0 Newell's Old Boys [3] 2021-05-14 00:30
Estadio: Estadio Dr. Nicolás Léoz Round: 4
Árbitro: Gustavo Tejera Home Manager: Daniel Garnero Away Manager: German Adrian Ramon Burgos
Head to Head
| Copa Sudamericana | 2021/04/30 00:30 | Newell's Old Boys v Club Libertad | W | 1-3 |
Home History
| Paraguay - Primera División | 2021/05/09 21:45 | Club Libertad v 12 de Octubre | W | 3-1 |
| Copa Sudamericana | 2021/05/06 22:15 | Club Libertad v Atlético GO | L | 1-2 |
| Paraguay - Primera División | 2021/05/03 23:00 | River Plate Asuncion v Club Libertad | W | 1-3 |
| Copa Sudamericana | 2021/04/30 00:30 | Newell's Old Boys v Club Libertad | W | 1-3 |
| Paraguay - Primera División | 2021/04/26 00:00 | Club Libertad v Club Nacional | D | 1-1 |
| Copa Sudamericana | 2021/04/23 00:30 | Club Libertad v Palestino | W | 2-0 |
| Paraguay - Primera División | 2021/04/18 21:45 | Cerro Porteño v Club Libertad | W | 0-3 |
| Copa Libertadores - Clasificación | 2021/04/15 00:30 | Atlético Nacional Medellín v Club Libertad | L | 4-1 |
Away History
| Argentina - Copa de la Liga Profesional | 2021/05/10 00:00 | Newell's Old Boys v Sarmiento | D | 1-1 |
| Copa Sudamericana | 2021/05/05 02:00 | Palestino v Newell's Old Boys | W | 0-1 |
| Argentina - Copa de la Liga Profesional | 2021/05/03 00:00 | Rosario Central v Newell's Old Boys | L | 3-0 |
| Copa Sudamericana | 2021/04/30 00:30 | Newell's Old Boys v Club Libertad | L | 1-3 |
| Argentina - Copa de la Liga Profesional | 2021/04/26 21:00 | Gimnasia La Plata v Newell's Old Boys | L | 2-1 |
| Copa Sudamericana | 2021/04/20 22:15 | Atlético GO v Newell's Old Boys | D | 0-0 |
| Argentina - Copa de la Liga Profesional | 2021/04/17 23:15 | Newell's Old Boys v Patronato de Paraná | W | 2-0 |
| Argentina - Copa de la Liga Profesional | 2021/04/12 22:00 | Lanús v Newell's Old Boys | W | 1-3 |