| NCAAF | 11/04 17:00 | 1 | Methodist Monarchs v Lagrange Panthers | L | 38-27 | |
| NCAAF | 10/28 19:00 | 1 | Lagrange Panthers v Brevard Tornados | L | 20-30 | |
| NCAAF | 10/21 17:00 | 1 | Maryville Scots v Lagrange Panthers | L | 26-6 | |
| NCAAF | 10/14 17:00 | 1 | Lagrange Panthers v Belhaven Blazers | L | 20-42 | |
| NCAAF | 10/07 17:00 | 1 | Lagrange Panthers v Nc Wesleyan Battling Bishops | L | 14-35 | |
| NCAAF | 09/30 17:00 | 1 | Southern Virginia Knights v Lagrange Panthers | L | 52-26 | |
| NCAAF | 09/23 17:00 | 1 | Lagrange Panthers v Huntingdon Hawks | L | 6-41 | |
| NCAAF | 09/16 16:00 | 1 | Ferrum Panthers v Lagrange Panthers | L | 13-10 | |
| NCAAF | 09/09 22:00 | 1 | Lagrange Panthers v Berry Vikings | L | 3-70 | |
| NCAAF | 11/12 19:00 | 1 | Huntingdon Hawks v Lagrange Panthers | L | 55-7 | |
| NCAAF | 11/05 17:00 | 1 | Lagrange Panthers v Southern Virginia Knights | L | 21-35 | |
| NCAAF | 10/29 00:00 | 1 | Belhaven Blazers v Lagrange Panthers | L | 70-16 |